Trial intelligence / Profile preview

PIM447 and ribociclib combinations with ruxolitinib in myelofibrosis

NL-OMON44750Phase 1Active, not recruiting

Sponsor
Novartis
Start
Oct 2016
Modality
Small Molecules
Countries
1
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Overview

Phase 1, open-label trial of PIM447, ribociclib and ruxolitinib in myelofibrosis (MF) (3 arms), sponsored by Novartis. Primary endpoint: Incidence of dose-limiting toxicities in cycle 1. Started Oct 2016; status: active, not recruiting.

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Drugs

PIM447ribociclibruxolitinib
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Conditions

myelofibrosis (MF)

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