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Tucatinib + trastuzumab + mFOLFOX6 versus standard-of-care mFOLFOX6-based first-line therapy in HER2-positive metastatic colorectal cancer
NL-OMON55981Phase 3Recruiting
- Sponsor
- Seagen Inc.
- Start
- Jan 2024
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules, DNA Intercalators/Alkylators → Nucleic Acid-Directed Small Molecules → Small Molecules
- Countries
- 1
01
Overview
Phase 3, randomised, open-label trial of tucatinib, trastuzumab, oxaliplatin, fluorouracil, folinic acid and 2 more in colorectal cancer (CRC) and metastatic colorectal adenocarcinoma (mCRC) (2 arms), sponsored by Seagen Inc. Primary endpoint: Progression-free survival. Started Jan 2024; status: recruiting.
02
Drugs
03
Conditions
colorectal cancer (CRC)metastatic colorectal adenocarcinoma (mCRC)
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