Trial intelligence / Profile preview

Tucatinib versus placebo with trastuzumab + pertuzumab maintenance after induction therapy in advanced HER2-positive breast cancer

NL-OMON60823Phase 3Active, not recruiting

Sponsor
Seagen Inc.
Start
Jun 2023
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
1
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Overview

Phase 3, randomised, double-blind trial in breast cancer comparing Tucatinib + trastuzumab + pertuzumab with Placebo + trastuzumab + pertuzumab (2 arms). Primary endpoint: Progression-free survival by investigator assessment. Started Jun 2023; status: active, not recruiting.

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Drugs

tucatinibtrastuzumabpertuzumab
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Conditions

breast cancer

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