Trial intelligence / Profile preview

TRAIN-5 neoadjuvant chemotherapy-free HER2-positive breast cancer study

NL-OMON61710Phase 2Not yet recruiting

Sponsor
Netherlands Cancer Institute
Start
Oct 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Small Molecules
Countries
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Overview

Phase 2, open-label, single-arm trial of zongertinib, trastuzumab and pertuzumab in breast cancer, sponsored by Netherlands Cancer Institute. Primary endpoint: Incidence and severity of adverse events. Planned start Oct 2026; status: not yet recruiting.

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Drugs

zongertinibtrastuzumabpertuzumab
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Conditions

breast cancer

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