Trial intelligence / Profile preview

RO7771950 versus tucatinib with trastuzumab + capecitabine in pretreated HER2-positive advanced or metastatic breast cancer

PACTR202605565481660Phase 2Not yet recruiting

Sponsor
Roche
Start
Apr 2026
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Irreversible Covalent Inhibitors → Covalent Small Molecules → Small Molecules
Countries
1
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Overview

Phase 2, randomised, open-label trial of RO7771950, tucatinib, trastuzumab and capecitabine in breast cancer (2 arms), sponsored by Roche. Primary endpoint: Progression-free survival in the full analysis set. Planned start Apr 2026; status: not yet recruiting.

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Drugs

RO7771950tucatinibtrastuzumabcapecitabine
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Conditions

breast cancer

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