Drug intelligence / Profile preview

Cantabell A

Development stage
Unknown
Lead developer
Chong Kun Dang Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Cantabell A (CKD-333) is a fixed-dose triple combination therapy developed by Chong Kun Dang Pharmaceutical for the simultaneous management of hypertension and dyslipidemia. The medication contains three active small molecule ingredients: amlodipine (a calcium channel blocker), candesartan cilexetil (an angiotensin II receptor blocker), and atorvastatin (an HMG-CoA reductase inhibitor). Amlodipine and candesartan work through complementary pathways to reduce blood pressure by inducing peripheral vasodilation and blocking the renin-angiotensin-aldosterone system, while atorvastatin lowers serum cholesterol levels by inhibiting the rate-limiting enzyme in hepatic cholesterol synthesis. Cantabell A was developed to improve patient compliance by consolidating multiple therapeutic regimens into a single daily tablet and has received regulatory approval following successful phase 3 clinical evaluation.

Brand names
Cantabell A
Other names
amlodipine + atorvastatin + candesartan cilexetil
02

Targets

CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)AGTR1 (Angiotensin II Type-1 receptor)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)

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