Drug intelligence / Profile preview

Compound Cortex Phellodendri

Development stage
Phase 4
Lead developer
Guangzhou Eighth People's Hospital
Administration
Topical
01

Overview

Compound Cortex Phellodendri is a Traditional Chinese Medicine (TCM) formulation, often prepared as a topical solution. It is composed of several herbal ingredients, including Huangbai (Cortex Phellodendri), Lianqiao (Forsythia suspensa), Jinyinhua (Lonicera japonica Thunb), Pugongying (Taraxacum mongolicum Hand. -Mazz), and Wugong (Scolopendra). The primary active constituent of Cortex Phellodendri, berberine, along with other compounds like jatrorrhizine, palmatine, obacunone, and obaculactone, contribute to its diverse pharmacological effects. These include anti-inflammatory, antimicrobial, antiviral, anticancer, antioxidant, and neuroprotective properties. It is traditionally used to clear heat, dry dampness, drain fire, eliminate steam, resolve toxins, and treat sores. Clinical applications are being explored for conditions such as diabetic foot ulcers, pustular sores, and skin and soft tissue infections.

Other names
Compound Huangbai Liquid Topical SolutionCompound Cortex Phellodendri LiquidCortex Phellodendri compound fluid
02

Targets

IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))PTGS2 (Prostaglandin-Endoperoxide Synthase 2)MAPK3 (Mitogen-activated protein kinase 1)IL1B (Interleukin-1 beta)NF-κB

Beyond the preview

Go deeper on Compound Cortex Phellodendri.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Compound Cortex Phellodendri.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call