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Cream vehicle-LEO Pharma-chronic hand eczema is the inactive placebo control used in clinical trials for delgocitinib cream (brand name Anzupgo), a topical pan-Janus kinase (JAK) inhibitor developed by LEO Pharma. The vehicle is a steroid-free cream formulation that matches the active drug's base excipients but contains no active medical ingredient. It was utilized as the comparator arm in the Phase 3 DELTA TEEN trial to evaluate the efficacy and safety of delgocitinib in adolescents aged 12-17 with moderate to severe chronic hand eczema. The vehicle serves to establish a baseline for treatment success and safety outcomes in the clinical development program for chronic hand eczema.
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