Drug intelligence / Profile preview

Gancao Nourish-Yin Decoction

Development stage
Preclinical
Lead developer
Zunyi Medical University Affiliated Hospital
Administration
Oral
01

Overview

Gancao Nourish-Yin Decoction is a Traditional Chinese Medicine (TCM) herbal formula being evaluated for its efficacy and safety in treating elderly patients with rheumatoid arthritis. Developed or utilized by the Affiliated Hospital of Zunyi Medical University, the decoction is typically administered orally in combination with standard Western medical treatments, such as methotrexate or other DMARDs. The formula is designed to nourish Yin, a TCM therapeutic strategy aimed at restoring systemic balance and alleviating chronic inflammatory symptoms. In clinical study settings, it is assessed for its ability to improve clinical response rates, reduce joint swelling and pain, and lower inflammatory markers like C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR).

Other names
Gancao Yangyin Tang
02

Targets

HSD11B2 (11β-HSD2)ESR2 (ERβ)GABRR (GABA-A receptor subunit rho)

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