lithospermum cream

Lithospermum cream is a topical herbal formulation derived from the root of *Lithospermum erythrorhizon* (known as Zicao in Traditional Chinese Medicine). It is primarily used for its anti-inflammatory, antioxidant, and wound-healing properties. The therapeutic effects are largely attributed to shikonin and its derivatives, which are naphthoquinone compounds that modulate inflammatory pathways. In clinical settings, it is being investigated as a treatment for hormone-dependent dermatitis (HDD), a condition resulting from the long-term misuse of topical corticosteroids. The cream serves as a non-steroidal alternative to agents like pimecrolimus, helping to alleviate symptoms such as erythema, burning, and itching while promoting the restoration of the skin barrier.

Other names

Zicao creamLithospermum erythrorhizon creamcomfrey creamGromwell root cream