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Qingdu Fang lotion

Development stage: Preclinical
Lead developer: Zhongshan Hospital of Traditional Chinese Medicine
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Vaginal

Overview

Qingdu Fang lotion is a Traditional Chinese Medicine (TCM) topical formulation developed by the Zhongshan Hospital of Traditional Chinese Medicine for the treatment of persistent high-risk human papillomavirus (HPV) infections. Administered intravaginally, the lotion is designed to facilitate HPV clearance by modulating the vaginal immune microenvironment and exerting local anti-inflammatory and antiviral effects. It has been evaluated in randomized clinical trials comparing its efficacy against recombinant human interferon α-2b gel in women with persistent high-risk cervical HPV infection, focusing on its ability to improve the local immune response and clear viral infection.

Other names: Qingdu lotionQingdufang lotion

Targets

JUN (Transcription factor Jun)STAT3 (Signal Transducer and Activator of Transcription 3)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)TP53 (Cellular Tumor Antigen p53 R175H)IL-6 (Interleukin 6)

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