Drug intelligence / Profile preview

qingqiao zhike decoction

Development stage
Preclinical
Lead developer
China Academy of Chinese Medical Sciences
Administration
Oral
01

Overview

Qingqiao Zhike Decoction is a Traditional Chinese Medicine (TCM) herbal formulation developed by Professor Gao Feng at Wangjing Hospital, China Academy of Chinese Medical Sciences. It is primarily utilized for the treatment of chronic cough, specifically targeting cases associated with Upper Airway Cough Syndrome (UACS) or "wind-induced" cough. The decoction is designed to "clear the orifices" (referring to the nasal and pharyngeal passages) and suppress the cough reflex. It is often evaluated in clinical settings alongside other specialized TCM regimens such as Zhisou Guomin Decoction and Beimu Zhizhu Decoction to compare their efficacy against standard conventional drug therapies. The formulation follows the TCM principle of combining disease differentiation with syndrome differentiation to provide personalized treatment for respiratory conditions.

Other names
Qingqiao Zhike Tang清窍止咳汤
02

Targets

STAT3 (Signal Transducer and Activator of Transcription 3)JUN (Transcription factor Jun)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)TP53 (Cellular Tumor Antigen p53 R175H)IL-6 (Interleukin 6)

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