Shenzhen Univ. Medical School GSK-3β/QC compound 2

Shenzhen Univ. Medical School GSK-3β/QC compound 2: sourced facts only. name: "Interestingly, compounds containing 5-methyl imidazole exhibited stronger GSK-3β-specific inhibitory activity (2, IC50 = 0.0021 μM), and the electron-withdrawing group and 2' and 3' substitution were favorable."; target: "Interestingly, compounds containing 5-methyl imidazole exhibited stronger GSK-3β-specific inhibitory activity (2, IC50 = 0.0021 μM), and the electron-withdrawing group and 2' and 3' substitution were favorable."; target: "Based on the primary screening, the introduction of 5-methyl imidazole at one side of the molecule did not enhance the QC-specific inhibitory activity of these hybrids (2, IC50 = 1.22 μM), although the potency was increased by 2' substitution on the maleimide motif at the other side of the molecule."; developer: "School of Pharmacy, Shenzhen University Medical School, Shenzhen 518055, China."