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Supportan
- Development stage
- Unknown
- Lead developer
- Fresenius Kabi
- Modality
- Small Molecules, Recombinant Proteins and Enzymes
- Administration
- Oral
01
Overview
Supportan is a high-energy, high-protein oral nutritional supplement enriched with omega-3 fatty acids (specifically eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from fish oil), fiber, and antioxidants. Developed by Fresenius Kabi, it is primarily indicated for the dietary management of patients with chronic inflammatory conditions, such as cancer cachexia, who are at risk of disease-related malnutrition. In clinical research, Supportan has been investigated for its potential to reduce hepatic steatosis and improve insulin sensitivity in morbidly obese patients prior to bariatric surgery. Its mechanism involves the modulation of lipid metabolism and inflammatory pathways, primarily through the action of its omega-3 fatty acid components on peroxisome proliferator-activated receptors (PPARs) and inflammatory mediators.
- Brand names
- SupportanSupportan Drink
02
Targets
PPARA (Peroxisome proliferator-activated receptor alpha)PPARG (Peroxisome proliferator-activated receptor gamma)
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