Trial intelligence / Profile preview

SMART-JIA

2025-520923-25-00Phase 3Authorised

Sponsor
Duke Clinical Research Institute
Start
Jun 2026
Modality
Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes, Small Molecules, Monoclonal Antibodies → Antibody-Based Therapeutics
Countries
4
01

Overview

Phase 3, open-label trial of adalimumab, etanercept, abatacept, tocilizumab and tofacitinib in juvenile idiopathic arthritis (JIA) (3 arms), sponsored by Duke Clinical Research Institute. Primary endpoint: Minimal disease activity at Month 6. Planned start Jun 2026; status: authorised.

02

Drugs

adalimumabetanerceptabatacepttocilizumabtofacitinib
03

Conditions

juvenile idiopathic arthritis (JIA)

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