Trial intelligence / Profile preview

Ceftriaxone and Doxycycline in Seropositive Chronic Lyme Disease

NCT00001101Phase 3

Key facts

Status
Completed
Primary completion
Mar 2001
Countries
1
Sponsor
National Institute of Allergy and Infectious Diseases
Modality
Reversible Covalent Inhibitors
Conditions
Lyme disease
01

Overview

Phase 3, randomised, double-blind trial of ceftriaxone and doxycycline in Lyme disease (2 arms), sponsored by National Institute of Allergy and Infectious Diseases. Status: completed.

02

Design

2 arms
Study design
RandomizedDouble-blind
  • Antibiotic therapy

    Ceftriaxone IV for 30 days followed by doxycycline orally for 60 days

  • Placebo

    Placebo IV for 30 days followed by placebo orally for 60 days

03

Who it enrols

Adults with seropositive chronic Lyme disease, documented history of acute Lyme disease and prior antibiotic treatment, with symptoms persisting for 6 months to 12 years.

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