Full results & analysis
Available in the Gosset platform where reported.
Trial intelligence / Profile preview
Alendronate and Aloe Vera Gel for Chronic Periodontitis with Furcation Defects
NCT03204097Phase 3
Key facts
- Status
- Completed
- Start
- Mar 2016
- Primary completion
- Feb 2017
- Sponsor
- Government Dental College and Research Institute
- Modality
- Transdermal Patches, Hydrogel Systems, Small Molecules
- Conditions
- chronic periodontitis
01
Overview
Phase 3, randomised, double-blind trial of alendronate and aloe vera gel in chronic periodontitis, sponsored by Government Dental College and Research Institute. Started Mar 2016; status: completed.
02
Design
- Study design
- RandomizedDouble-blind
03
Who it enrols
Systemically healthy patients with chronic periodontitis and mandibular class II furcation defects, PD ≥ 5mm, and horizontal PD ≥ 3mm.
04
Registry description
Alendronate (ALN), commonly use bisphosphonates is proposed to have osteostimulative properties in vivo and in vitro, as shown by an increase in the matrix formation, and acts as a potent inhibitor of bone resorption. AV widely known for its wound healing, analgesic, antioxidant, antibacterial, antiviral, antifungal, immune boosting and significant anti-inflammatory properties. The present study aims to explore the efficacy of 1% ALN and AV gel as a local drug delivery as an adjunct to scaling and root planing (SRP) for the treatment of degree II furcation defects
Beyond the preview
Go deeper on NCT03204097.
Full results, competitive context and analysis are in the Gosset platform.
Competitive context
Available in the Gosset platform where reported.
Bring the full picture into focus.
See how Gosset can support your research on NCT03204097.