Full results & analysis
Available in the Gosset platform where reported.
Trial intelligence / Profile preview
Ondansetron + dexamethasone + dimenhydrinate vs ondansetron + dexamethasone for prevention of postoperative nausea and vomiting after gynecologic laparoscopic surgery
TCTR20210128001Phase 4
Key facts
- Status
- Completed
- Start
- Dec 2019
- Countries
- 1
- Sponsor
- Faculty of Medicine, Khon Kaen University
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Small Molecules
- Conditions
- postoperative nausea and vomiting (PONV)
01
Overview
Phase 4, randomised, double-blind trial in postoperative nausea and vomiting (PONV) comparing ondansetron + dexamethasone + dimenhydrinate with ondansetron + dexamethasone (2 arms). Primary endpoint: incidence of postoperative nausea and vomiting. Started Dec 2019; status: completed.
02
Design
2 arms- Study design
- RandomizedDouble-blind
ondansetron + dexamethasone + dimenhydrinate
Participants receive a combination of ondansetron, dexamethasone, and dimenhydrinate for prophylaxis of postoperative nausea and vomiting.
ondansetron + dexamethasone
Participants receive ondansetron and dexamethasone without dimenhydrinate for prophylaxis of postoperative nausea and vomiting.
03
Who it enrols
Adult women undergoing gynecologic laparoscopic surgery in Thailand, generally healthy apart from the surgical condition, with pregnant women excluded.
04
Endpoints
Primary
incidence of postoperative nausea and vomiting
Beyond the preview
Go deeper on TCTR20210128001.
Full results, competitive context and analysis are in the Gosset platform.
Competitive context
Available in the Gosset platform where reported.
Bring the full picture into focus.
See how Gosset can support your research on TCTR20210128001.