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Xin-Li-Fang

Development stage: Unknown
Lead developer: The Second Affiliated Hospital of Guangzhou University of Chinese Medicine
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Xin-Li-Fang is a Traditional Chinese Medicine (TCM) herbal formula developed as a granule formulation for the treatment of chronic heart failure (CHF). Developed by the Second Affiliated Hospital of Guangzhou University of Chinese Medicine, the formula is typically used as an adjunct to guideline-directed medical therapy (GDMT). Based on TCM principles, Xin-Li-Fang is designed to tonify Qi and promote blood circulation, addressing the complex pathophysiology of heart failure through pleiotropic effects. Clinical evaluation has focused on its efficacy and safety in improving cardiac function and clinical symptoms in adult patients with chronic heart failure.

Brand names: xinli fang
Other names: Xin-Li-Fang granulesXinlifang

Targets

NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)AQP1 (Aquaporin-1)AGTR1 (Angiotensin II Type-1 receptor)

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