Trial intelligence / Profile preview

Atenolol, Perindopril, and Verapamil in Marfan Syndrome

NCT01295047Phase 4

Key facts

Status
Completed
Start
Jul 2006
Primary completion
Dec 2007
Countries
1
Sponsor
Cardiff University
Modality
Small Molecules
Conditions
Marfan syndrome (MFS)
01

Overview

Phase 4, randomised, double-blind trial of atenolol, perindopril and verapamil in Marfan syndrome (MFS), sponsored by Cardiff University. Primary endpoint: Central Arterial Pressure at 18 weeks. Started Jul 2006; status: completed.

02

Design

Study design
RandomizedDouble-blind
03

Who it enrols

Patients aged 16-60 with Marfan syndrome, excluding those with prior aortic surgery/dissection, severe valvular disease, or large aortic diameter.

04

Endpoints

Primary

  • Central Arterial Pressure

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