Drug intelligence / Profile preview

camrelizumab + rh-endostatin

Development stage
Phase 2
Lead developer
Hengrui Therapeutics
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

camrelizumab + rh-endostatin is a combination therapy for advanced non-small cell lung cancer (NSCLC). Camrelizumab is an anti-PD-1 monoclonal antibody that blocks the PD-1/PD-L1 immune checkpoint, enhancing T-cell-mediated antitumor immunity. Rh-endostatin (recombinant human endostatin) is an antiangiogenic drug that inhibits tumor angiogenesis by targeting vascular endothelial cells, promoting vascular normalization and improving the tumor immune microenvironment. The combination has shown promising efficacy and safety in clinical studies for advanced NSCLC.

Other names
camrelizumab plus rh-endostatinrh-endostatin plus camrelizumab
02

Targets

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