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mycophenolate mofetil + prednisone + treprostinil
- Development stage
- Unknown
- Lead developer
- United Therapeutics
- Modality
- Small Molecules
- Administration
- Oral, Intravenous, Subcutaneous, Inhalation
01
Overview
A combination therapy consisting of mycophenolate mofetil (an immunosuppressant), prednisone (a corticosteroid), and treprostinil (a prostacyclin vasodilator). Mycophenolate mofetil works by weakening the immune system to prevent organ rejection after transplantation. Prednisone is a corticosteroid with immunosuppressive and anti-inflammatory properties. Treprostinil is a prostacyclin analog that relaxes blood vessels, particularly in the lungs, improving blood flow in patients with pulmonary arterial hypertension.
02
Targets
PTGIR (Prostanoid IP Receptor)PTGER2 (Prostaglandin E2 receptor EP2)GR (Glucocorticoid receptor)PTGDR (Prostanoid DP1 receptor)IMPDH (Inosine-5'-monophosphate dehydrogenase 1)
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